Contact information 1800 8330166 phone physician requests should be directed to. Cvs caremark administers the prescription benefit plan for the patient identified. Each of the side effects above was reported in 10% or greater of patients treated with zoledronic acid. Novartis reclast patient information sheet keyword after analyzing the system lists the list of keywords related and the list of websites with related content, in addition you can see which.
Reclast is used to treat or prevent osteoporosis caused by menopause, steroid use, or gonadal failure. Zoledronic acid zoledronic acid this product information is intended only for residents of the united states. Zoledronic acid intravenous route description and brand. Physicians and other health care professionals are encouraged to consult other sources and confirm the information. Patient has received randolph health reclast information sheet 9.
Reclast zoledronic acid sometimes called zoledronate is a bisphosphonate medicine that alters bone formation and breakdown in the body. Patients receiving zometa should not receive reclast 5. Description zoledronic acid reclast, zometa is a bisphosphonate. Zoledronic acid zometa, reclast prior auth criteria proprietary information. Alendronate fosamax, risedronate actonel, and ibandronate boniva. The related drug information index provides comprehensive access to all drug information related to a specific drug types of content include full prescribing information, drug summaries, full prescribing information. Medications administered by a healthcare professional most insurance companies cover medications administered by a healthcare professional in a medical office or hospital such as a drug that is given by intravenous infusion. For more information, ask your doctor or pharmacist. Please also read the package leaflet of zoledronic acid 5 mg for more information.
May 08, 2020 these are not all the possible side effects of reclast. A single dose of reclast should not exceed 5 mg and the. This medication guide does not take the place of talking with your doctor about your medical condition or treatment. These include osteoporosis, high blood calcium due to cancer, bone breakdown due. Zoledronic acid reclast zoledronic acid is approved for the prevention and treatment of osteoporosis in postmenopausal women. In a study in patients with cancer and bone metastases, increasing the infusion time of a 4 mg dose of zoledronic acid from 5 minutes n5 to 15 minutes n7 resulted in a. Most people with low blood calcium levels do not have symptoms, but some people may have symptoms. Zoledronic acid reclast national osteoporosis foundation. Please see indications and important safety information on page 2, and the accompanying prolia full prescribing information, including medication guide.
Sep 01, 2019 reclast should not be given if the patient is pregnant or plans to become pregnant, or if she is breastfeeding see warnings and precautions 5. Reclast and zometa are two different brands of zoledronic acid. Nov 18, 2016 zoledronic acid reclast, aclasta is an intravenous, highly potent aminobisphosphonate approved worldwide, including in the usa, eu and japan for use in patients with primary or secondary osteoporosis or low bone mass approved indications vary between countries. This patients benefit plan requires prior authorization for certain medications in order for the drug to be covered.
Zoledronic acid is a powerful type of bisphosphonate. This fax may contain medical information that is privileged and. Its molecular formula is c 5 h 10 n 2 o 7 p 2 h 2 o and a molar mass of 290. A patient that is already receiving zometa should not be treated with reclast. Physicians and other health care professionals are encouraged to consult other sources and confirm the information contained within this site. What you need to know about paying for your osteoporosis medications. Your low blood calcium must be treated before you take reclast. By completing and faxing this form, you represent that your patient is aware of the disclosure of their personal health information to amgen and its agents for. Zoledronic acid clearance was independent of dose but dependent upon the patient s creatinine clearance. Read the medication guide and, if available, the patient information leaflet provided by your pharmacist before you start using this product and each time you. Zoledronic acid has been shown to prevent the bone loss seen in 62 adult patients who had received a liver transplant for chronic liver disease. Side effects are listed in the following table in the order in which they may occur. Call your doctor for medical advice about side effects. In preclinical models, zoledronic acid prevents tumour adhesion to the bone, induces tumour cell apoptosis, and inhibits angiogenesis.
Reclast zoledronic acid dose, indications, adverse. If you have any further questions, ask your doctor or pharmacist. Zoledronic acid should not be prescribed if the patient is receiving zometa. Zoledronic acid reclast zoledronic acid is a bisphosphonate prescribed to prevent or treat osteoporosis or pagets disease. Intravene reclast zoledronic acid infusion orders rev 102018 please fax this form along with a copy of insurance cards and clinical documentation to 4344555531 or call 14349473900 ext. If you have questions or doubts, talk to your doctor, nurse or pharmacist. Reclast and zometa contain the same active ingredient. Zoledronic acid is structurally similar to pamidronate. Affected cytochrome p450 isoenzymes and drug transporters. You should not receive reclast if you are already receiving zometa.
Zoledronic acid 5 mg is a medicine intended for patients. Insurance verification and prior authorization form. What is the most important information i should know about reclast. Zoledronic acid reclast is a biologic reference guide with prescribing information, dosage. Reclast is contraindicated in patients with creatinine clearance less than 35 mlmin and in those with evidence of acute renal impairment see contraindications 4. See 17 for patient counseling information and medication guide. Reclast is the brand name of the prescription drug zoledronic acid, used to treat and prevent osteoporosis a condition in which bones become weak and may break easily it may also be used to. Reclast is used to treat osteoporosis caused by menopause, steroid use, or gonadal failure. Read the medication guide and, if available, the patient information leaflet provided by your pharmacist before you start using this product and each. Zoledronic acid can protect and strengthen bones in people with myeloma or some types of cancer that have spread to the bone. Zoledronic acid was initiated within 90 days of surgical repair.
Reclast fda prescribing information, side effects and uses. Information for the user prolia 60 mg solution for injection in prefilled syringe denosumab read all of this leaflet carefully before you start using this medicine because it contains important information for you. It is given as a onceyearly infusion for osteoporosis in patients aged 70 years of age or older with a bone mineral density tscore of 2. It is also used in the treatment of multiple myeloma andor bone. Rarely patients have reported severe bone, joint and muscle pain that begins from 1 day to one month after starting any bisphosphonate, including zolendronic. You can ask your doctor or pharmacist for information about reclast that is written for health professionals.
See 17 for patient counseling information and medication. Reclast is indicated for treatment of osteoporosis in postmenopausal women. Unlike other common bisphosphonates that are taken by mouth, reclast bypasses the stomach because it is an infusion into the bloodstream. Zoledronic acid aclasta for osteoporosis nps medicinewise. See what others have said about reclast, including the effectiveness, ease of use and side effects. The 0 to 24 hour renal clearance of zoledronic acid was 3. Zoledronic acid reclast order form infusion solutions, inc. Reclast is also used to treat pagets disease of bone. Drink two 2 glasses of fluids, such as water, within a few hours before receiving reclast to help prevent kidney problems 3. Zoledronic acid is indicated for the prevention of skeletalrelated events sres such as pathological fractures, bone pain, spinal compression, need for bone radiation, or surgery in patients. The rate of any new clinical fracture minus digital or facial fractures or fractures in abnormal bone was reduced significantly in patients receiving zoledronic acid 8.
Reclast patient information handout keyword found websites. Information for the user zoledronic acid accord 4 mg5 ml concentrate for solution for infusion zoledronic acid read all of this leaflet carefully before you are given this medicine because it contains important information. If you have low blood calcium before you start taking reclast, it may get worse during treatment. The clinical information contained in the via pathways and via portal are intended as a supplement to, and not a substitute for, the knowledge, expertise, skill, and judgment of physicians, pharmacists and other healthcare professionals involved with patient care at client facilities. All information contained within the johns hopkins arthritis center website is intended for educational purposes only. Zoledronic acid injection is used to treat hypercalcemia high levels of calcium in the blood that may occur in patients with some types of cancer.
Medication guide zoledronic acid injection what is the most. This can slow bone loss and may help prevent bone fractures. Patient has been instructed to drink at least 2 glasses of fluids within a few hours prior to infusion zoledronic acid reclast 5 mg in 100 mlto be infused over 30 minutes in the special procedures unit of the outpatient center provide patient information sheet to patient. This leaflet does not take the place of discussions with your doctor. If zoledronic acid is chosen, there are sufficient data in men with crpc to support dosing of zoledronic acid every 12 weeks medicationrelated osteonecrosis of the jaw in patients with. This medicine is for use when you have a high risk of bone fracture due to osteoporosis. Highlights of prescribing information may worsen during. Zoledronic acid is approved for the prevention and treatment of osteoporosis in postmenopausal women. As a biologic drug, it is synthetic and closely resembles naturallyoccurring antibodies in the body. See important reminder at the end of this policy for important regulatory and legal information. Zoledronic acid reclast zoledronic acid is a bisphosphonate. Ibandronate boniva and zoledronic acid reclast, zometa are bisphosphonates. Reclast patient assistance program reclast patient assistance program novartis. Zoledronic acid monohydrate is a white crystalline powder.
All of the drugs you mention are used to treat postmenopausal women with osteoporosis, although theyre in different drug classes. Patients must receive adequate hydration prior to the administration of reclast. Reclast contains zoledronic acid, a bisphosphonic acid which is an inhibitor of osteoclastic bone resorption. This medication guide summarizes the most important information about reclast. Reclast reclast zoledronic acid injection read the medication guide that comes with reclast before you start taking it and each time you get a refill. Zoledronic acid, also known as zoledronate, is a medication used to treat a number of bone diseases. Tell your doctor denosumab prolia is a biologic medication used to prevent fragile bones, also known as osteoporosis, and bone fractures. Novartis reclast patient information sheet keyword after analyzing the system lists the list of keywords related and the list of websites with related content, in addition you can see which keywords most interested customers on the this website. Uptodate, electronic clinical resource tool for physicians and patients that provides information on adult primary care and internal medicine, allergy and immunology, cardiovascular medicine, emergency medicine, endocrinology and diabetes, family medicine, gastroenterology and hepatology, hematology, infectious diseases, nephrology and.
Zoledronic acid clearance was independent of dose but dependent upon the patients creatinine clearance. Dec 23, 2019 reclast zoledronic acid sometimes called zoledronate is a bisphosphonate medicine that alters bone formation and breakdown in the body. It is also approved to increase bone mass in men with osteoporosis and for the prevention of new clinical fractures in patients who have recently had a lowtrauma hip fracture. May 08, 2020 reclast and zometa are two different brands of zoledronic acid. Novartis reclast patient information sheet keyword found. Reclast zoledronic acid injection side effects, images. Im looking for information on prolia and reclast as alternatives to boniva. Reclast may lower the calcium levels in your blood. You can ask your doctor or pharmacist for information. In postmenopausal women with osteoporosis, diagnosed by bone mineral density bmd or prevalent vertebral fracture, reclast reduces the incidence of fractures hip.
There have been reports of bronchoconstriction in aspirinsensitive patients receiving bisphosphonates, including reclast. Reclast contains the same active ingredient found in zometa. Unlike other common bisphosphonates that are taken by. Importance a proofofprinciple study suggested that intravenous zoledronic acid may reduce knee pain and the size of bone marrow lesions in people with knee osteoarthritis, but data from large trials are lacking objective to determine the effects of intravenous zoledronic acid on knee cartilage volume loss in patients. Highlights of prescribing information tymlos safely and.
If you would like more information, talk with your doctor. You may eat normally before receiving your infusion. It is also approved to increase bone mass in men with osteoporosis and for the prevention of new clinical fractures in patients. Also, read the leaflet each time you refill your prescription, just in case anything has changed. Medication guide zoledronic acid injection what is the. Restricted access do not disseminate or copy without approval. Dailymed zoledronic acid zoledronic acid injection. Select one of the links below to download the application or go to the program site for more information. None zoledronic acid does not inhibit any cyp450 enzymes in vitro. Zoledronic acid is used to treat high levels of calcium in the blood hypercalcemia. Drink two 2 glasses of fluids, such as water, within a few hours. Effect of intravenous zoledronic acid on tibiofemoral. Highlights of prescribing information these highlights do not include all the information needed to use reclastsafely and effectively. Its high affinity to and long halflife in bone, and long duration of action, allow for onceyearly administration, which has.
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